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The following 3 experts are listed against your chosen search criteria of:
Expertise: Hypertension

Dr David Collier
I am now based at the Heart Centre at Barts, and ran the Anglo-Scandinavian Cardiac Outcome Trial (ASCOT) team for Professor Caulfield at Barts/London, which broke the national record for recruitment into such a trial (recruiting 1157 patients). As top academic recruiters for several studies across over a decade, which has contributed to high-impact work such as ILLUMINATE, with 148 patients (NEJM 2007 Barter, Caulfield et al ). ASCOT became a landmark trial and precipitated the development of joint NICE/BHS guidelines for hypertension after the publication of the Blood Pressure Lowering Arm (BPLA) in the Lancet in 2005 (prior to this time there had been separate NICE and BHS (British Hypertension Society) Guidelines on the treatment of hypertension in the UK- which had been unhelpful. ASCOT impacted the lipid guidance from NICE on statin use in primary prevention of ischaemic heart disease and stroke- bringing routine use of statins for people at elevated absolute risk, regardless of starting levels of cholesterol.

Prof Patricia Munroe
My research is focused on elucidating the genetic and molecular basis of hypertension and cardiac arrhythmias. I co-lead several international complex genetic disease consortia. Using meta-analysis of genome-wide association studies (GWAS) and large-scale candidate gene studies I have discovered over 30 genetic loci associated with hypertension over the past 3 years.

Dr Julian Shiel
I am a Research Fellow for ASCOT (Anglo-Scandinavian Cardiac Outcomes Trial), the first major study evaluating combinations of modern anti-hypertensive drugs compared with older drugs. It also aims to assess the effect of cholesterol lowering in hypertensive patients.

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