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Expertise: Gene Therapy
Dr David Gould
I have a keen interest in the development of gene based or genetically engineered treatments for disease. I have made progress in developing gene therapy vectors that permit controlled expression of a therapeutic gene by utilising the tetracycline system of gene expression. Gene therapies could offer improved and innovative approaches to disease treatment through both local production and linking expression levels of therapeutic molecules to degree of disease activity.
Prof Rizgar Mageed
My studies are focussed on defining the molecular basis of humoral autoimmunity in patients with rheumatic diseases. These studies explore how abnormalities in intracellular signaling pathways in lymphocytes promote hyperactivity and autoimmunity. Other areas of research include stem-cell based gene therapy, antibody genes and intracellular signalling.